- Well researched ingredients
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Mind Lab Pro
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October 09, 2023
The demand for nootropics, or cognitive-enhancing supplements, has really taken off in recent years. Nootropics, a word coined by Dr. Corneliu E. Giurgea, refers to a broad spectrum of substances intended to enhance cognitive abilities, including memory, learning, focus, mental clarity, and creativity. It is also claimed that some nootropics may delay age-related cognitive decline.
A growing body of research confirms the benefits of a range of nootropic ingredients in terms of boosting mental performance and their ability to treat memory disorders, such as Alzheimer's, Parkinson's, and Huntington's diseases (1).
In this article, we put two of the most popular nootropics on the market, NooCube and Mind Lab Pro, in a head-to-head comparison. Join us as we analyze their formulations, evaluate their potency, and give our take on which is best for various target audiences.
NooCube is a brain health supplement from the well-known Scottish health supplement company Wolfson Brands. This is a stimulant-free supplement that contains no caffeine.
NooCube combines vitamins like B1, B7, and B12 with herbal extracts such as Bacopa Monnieri, L-tyrosine, Cat's Claw, Oat Straw, L-theanine, Alpha GPC, Huperzia Serrata, and carotenoids like Lutemax 2020. Additionally, it incorporates compounds like resveratrol and pterostilbene, which may contribute to mental well-being. NooCube does a generally good job of aligning its dosages with scientific recommendations.
The benefits touted for NooCube encompass sharper focus, memory enhancement, improved attention span, stress reduction, reduced mental fatigue, and support for the eye-brain connection. Whether you're a student, athlete, or professional seeking to bolster productivity, NooCube's blend of research-backed ingredients may provide the cognitive edge you're after.
MindLab Pro, a cognitive enhancer developed by Opti Nutra based in New Jersey, USA, stands out as a universal nootropic supplement designed to enhance various facets of cognitive function rather than targeting specific areas. This comprehensive approach aims to optimize mental performance across the following cognitive dimensions:
Here's a breakdown of the ingredients and dosages in MindLab Pro:
As with NooCube, this is a stimulant-free supplement.
You'd expect leading nootropics based on research findings to have common ingredients. That's the case here, with five common compounds in NooCube and MindLab Pro. Let's check them out:
NooCube includes choline, which plays a crucial role in brain function and the synthesis of neurotransmitters. MindLab Pro features citicoline, a source of choline that can enhance cognitive function by supporting acetylcholine levels in the brain. This neurotransmitter is essential for memory and learning.
Both forms of choline provide 250 mg of their respective form of choline.
Bacopa Monnieri is one of the critical ingredients in NooCube, known for its potential to enhance memory and cognitive function. MindLab Pro also incorporates Bacopa Monnieri, which has a traditional reputation for supporting cognitive health, particularly memory and information processing speed.
NooCube provides 250 mg of Bacopa monnieri in a 12:1 concentrated extract, enhancing potency beyond the 250 mg. This compares to the 150 mg in Mind Lab Pro.
NooCube contains L-tyrosine, an amino acid used by the body to produce neurotransmitters like dopamine and norepinephrine. It can enhance cognitive performance, especially in demanding situations. MindLab Pro includes N-Acetyl L-Tyrosine, a form of tyrosine that is more soluble and bioavailable. It provides similar cognitive benefits, including improved focus and stress reduction.
There is 250 mg of L-tyrosine in NooCube, compared with 175 mg of n-acetyl tyrosine in Mind Lab Pro. This is a more soluble and bioavailable form of tyrosine, so it balances out the lower dose.
NooCube is enriched with L-theanine, an amino acid primarily found in tea leaves. L-theanine promotes relaxation, attention, and cognitive function. MindLab Pro also contains L-theanine, known for its calming and focus-enhancing properties. It can help reduce stress and anxiety while supporting mental clarity.
You get 100 mg of L-theanine in both products.
NooCube includes Vitamin B12, essential for proper brain function, mood regulation, and cognitive health. MindLab Pro features Vitamin B12 as well, contributing to cognitive well-being and overall brain function.
NooCube contains 2.5 mcg of Vitamin B12 compared with 7.5 mcg in Mind Lab Pro. Both doses are relatively low compared to clinical doses used to treat vitamin B deficiency-related cognitive deficits.
Let's now focus on the ingredients that make these supplements different from one another, starting with NooCube:
The people behind NooCube are constantly analyzing their nootropic formula and are not afraid to tweak the ingredients in line with new research. Here are the unique ingredients at the time of writing (October 2023):
Thiamine, or vitamin B1, is essential to the neurological system and brain health. It aids in converting glucose into energy, which the brain and neurological system need to perform at their best. Neurological problems like fatigue, forgetfulness, and disorientation can result from thiamine deficiency. Thiamine supplementation may help with mood enhancement, anxiety and depression reduction, and cognitive function enhancement (2).
Biotin, commonly known as Vitamin B7, is an essential B-complex vitamin for good general health. It contributes to how food is transformed into energy. Limited study has been done on the specific cognitive benefits of biotin (3). However, deficiencies can cause symptoms like weariness, sadness, and hallucinations. Maintaining a sufficient intake of biotin may aid in the prevention of these symptoms.
Cat's Claw is a herb that may have anti-inflammatory and antioxidant effects. According to some studies, cat's claw extract may improve mental health, possibly reducing symptoms of anxiety and sadness (4)
Panax Ginseng is an herbal root with adaptogenic properties. It is popular for relieving stress and increasing your energy levels (5). Ginseng has long been used to enhance mental clarity, reduce fatigue, and enhance cognitive function.
Marigold flower extract delivers an excellent source of two key carotenoids: lutein and zeaxanthin. While generally associated with eye health, these two compounds may also support brain health (6). More study is needed to state with certainty that this ingredient benefits brain health.
Trans-resveratrol is derived from fruits and vegetables, as well as red grapes. It has potent anti-inflammatory and antioxidant qualities and is believed to boost memory and learning (7).
Pterostilbene comes from blueberries and possesses antioxidant and anti-inflammatory qualities that may positively impact memory and learning(8).
Let's now turn to the unique ingredients that set MindLab Pro apart:
Vitamin B6 is vital in the production of neurotransmitters in brain cells. It is responsible for manufacturing dopamine, GABA, and serotonin, all essential for brain function and mood control (9).
Vitamin B9, known as folate, is needed to synthesize DNA and neurotransmitters and for cell division. It is essential for brain function and healthy cognitive development (3).
Lion's mane mushroom is a medicinal mushroom that may improve cognition. It has ingredients called hericenones and erinacines, which have been studied for their potential to be neuroprotective and neuro-regenerative (10).
According to some research, Lion's mane mushroom extract helps the brain cells function, assists nerve growth and regeneration, and possibly improves memory, focus, and brain energy.
Phospholipidylserine is an important phospholipid that helps maintain nerve cells' functionality and structure. It may also improve cognitive function, memory, and attention, particularly in older people (11).
Rhodiola Rosea is an adaptogenic plant that is known to relieve stress. It helps the body adapt to psychological and emotional stress (12).
Maritime Pine Bark Extract contains several bioactive substances, such as proanthocyanidins, potent antioxidants that fight oxidative stress and lessen the harm done to the body and brain by free radicals (13).
Mind Lab Pro targets a wide range of individuals looking to optimize their cognitive performance and overall brain health. Its target audience includes:
Noocube caters to a specific set of audiences focused on improving productivity, reducing stress, and enhancing cognitive performance. Its target audience includes:
While both NooCube and Mind Lab Pro contain a number of natural components and are generally considered safe for most people, each supplement has its own distinct adverse effects linked to particular ingredients. It's important to remember that these side effects are relatively uncommon and moderate and that each person may react differently.
Huperzine-A: At high doses, Huperzine-A might have adverse effects such as nausea, vomiting, diarrhea, and sweating. Additionally, it could cause cramping, twitching, and restlessness.
Both NooCube and Mind Lab Pro offer a range of natural ingredients designed to enhance cognitive function and support overall brain health. However, choosing these two brain supplements depends on individual needs, goals, and sensitivities.
NooCube is an excellent choice for:
Mind Lab Pro is recommended for:
Both supplements have their unique strengths and ingredients. NooCube specializes in addressing specific lifestyle needs, such as athletic performance, academic demands, and multitasking. On the other hand, Mind Lab Pro offers a comprehensive approach to cognitive enhancement and brain health, making it suitable for a broader audience looking to optimize mental performance.
For more cognitive-enhancing supplements, read the 7 Best NootropicsTo Maximize Your Brain's Potential.
Suliman NA, Mat Taib CN, Mohd Moklas MA, Adenan MI, Hidayat Baharuldin MT, Basir R. Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic. Evid Based Complement Alternat Med. 2016;2016:4391375. doi: 10.1155/2016/4391375. Epub 2016 Aug 30. PMID: 27656235; PMCID: PMC5021479.
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Robby. (2023, May 8). Cat’s Claw and the brain: Could this revolutionize care for cognitive decline? Dr. Lam Coaching - World Renowned Authority on Adrenal Fatigue Recovery. https://www.drlamcoaching.com/blog/cats-claw-and-the-brain/
Vogler BK, Pittler MH, Ernst E. The efficacy of ginseng: a systematic review of randomised clinical trials. 1999. In: Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet]. York (UK): Centre for Reviews and Dissemination (UK); 1995-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK67758/
Bio-gen marigold extract improves cognitive function. Nutraceutical Business Review. (n.d.). https://www.nutraceuticalbusinessreview.com/news/article_page/Bio-gen_marigold_extract_improves_cognitive_function/199112
Evans HM, Howe PR, Wong RH. Effects of resveratrol on cognitive performance, mood and cerebrovascular function in post-menopausal women; a 14-week randomised placebo-controlled intervention trial. Nutrients. (2017) 9:27.
McCormack D, McFadden D. A review of pterostilbene antioxidant activity and disease modification. Oxid Med Cell Longev. 2013;2013:575482. doi: 10.1155/2013/575482. Epub 2013 Apr 4. PMID: 23691264; PMCID: PMC3649683.
Durrani D, Idrees R, Idrees H, Ellahi A. Vitamin B6: A new approach to lowering anxiety, and depression? Ann Med Surg (Lond). 2022 Sep 15;82:104663. doi: 10.1016/j.amsu.2022.104663. PMID: 36268413; PMCID: PMC9577631.
Lai PL, Naidu M, Sabaratnam V, Wong KH, David RP, Kuppusamy UR, Abdullah N, Malek SN. Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Int J Med Mushrooms. 2013;15(6):539-54. doi: 10.1615/intjmedmushr.v15.i6.30. PMID: 24266378.
Nawaz, Hadia. (2022). Effect of phosphatidylserine on cognitive function in the elderly: A systematic review and meta-analysis. 10.9721/KJFST.2022.54.1.52.
Ma GP, Zheng Q, Xu MB, Zhou XL, Lu L, Li ZX, Zheng GQ. Rhodiola rosea L. Improves Learning and Memory Function: Preclinical Evidence and Possible Mechanisms. Front Pharmacol. 2018 Dec 4;9:1415. doi: 10.3389/fphar.2018.01415. PMID: 30564123; PMCID: PMC6288277.
Daniells, S. (2015, December 17). Pine bark extract shows cognition for Boomers: Study. nutraingredients.com. https://www.nutraingredients.com/Article/2015/12/17/Pine-bark-extract-shows-cognition-for-Boomers-Study
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